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1,2,4-Oxadiazole ring–containing pyridylpyrazole-4-carboxamides: Synthesis and evaluation as novel insecticides of the anthranilic diamide family
Authors:Abdalla Khallaf  Ping Wang  Hui Liu  Shuping Zhuo  Hongjun Zhu
Institution:1. School of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo, China

Department of Applied Chemistry, College of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing, China;2. School of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo, China;3. Department of Applied Chemistry, College of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing, China

Abstract:Herein, we describe the preparation of pyridylpyrazole-4-carboxamides containing a 1,2,4-oxadiazole ring as novel anthranilic diamide derivatives and compare their insecticidal activities to that of chlorantraniliprole, a well-established potent insecticide. Biological activity tests reveal that all compounds had good insecticidal activities, with the most potent species achieving diamondback moth (Plutella xylostella) mortalities of 100% and 57% at concentrations of 400 and 200 μg mL−1, respectively.
Keywords:
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