Biosynthesis of Fe3O4-magnetic nanoparticles using clover leaf aqueous extract: Green synthesis of 1,3-benzoxazole derivatives |
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Authors: | Faezeh Shafaei Seyyed Ebrahim Babaei Ashraf Sadat Shahvelayati Fatemeh Honarmand Janatabadi |
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Institution: | 1. Faculty of Science, Department of Chemistry, East Tehran Branch, Islamic Azad University, Tehran, Iran;2. Department of Chemistry, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran;3. Department of Chemistry, Faculty of Science, Yadegar-e-Imam Khomeini (RAH), Shahre Rey Branch, Islamic Azad University, Tehran, Iran |
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Abstract: | In this research, magnetic Fe3O4-NP nanoparticles were synthesized employing a green biosynthetic procedure by reduction of ferric chloride solution with clover leaf water extract. The nanoparticles prepared via this biosynthesis method can potentially be valuable for different purposes such as organic synthesis. In this research, 1,3-benzoxazole derivatives were generated via a multicomponent reaction of α-bromo ketones, isothiocyanate, and propiolate in the presence of a catalytic amount of bio-Fe3O4 MNPs and sodium hydride in water at 50°C in good yields. The catalyst was reused five times with a minor decrease in its catalytic activity. |
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Keywords: | 1 3-benzoxazole alkyl (aryl) isothiocyanates clover leaf Fe3O4 MNPs isothiocyanates |
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