Design,synthesis, and characterization of some new benzimidazole derivatives and biological evaluation |
| |
| Authors: | Hakan Bektaş Bahar B. Sökmen Sinem Aydın Emre Menteşe Adile Bektaş Gamze Dilekçi |
| |
| Affiliation: | 1. Department of Chemistry, Art and Science Faculty, Giresun University, Giresun, Turkey;2. Department of Biology, Art and Science Faculty, Giresun University, Giresun, Turkey;3. Department of Chemistry, Art and Science Faculty, Recep Tayyip Erdogan University, Rize, Turkey |
| |
| Abstract: | A new series of benzimidazole derivatives ( 1-15 ) containing 1,2,4-triazole, 1,3,4-thiadiazole, 1,3,4-oxadiazole, and thiazolidinon rings have been synthesized. All new synthesized benzimidazole compounds were confirmed by 1H NMR, 13C NMR spectra, and LC-MS, and they were examined for their antioxidant and antimicrobial activities. Compounds 7 and 1 showed the highest and the lowest antioxidant activities, respectively. The lowest minimum inhibition concentration value found in compound 5 against Enterobacter aerogenes. |
| |
| Keywords: | |
|
|
