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Spectrofluorimetric method for the determination of piroxicam and pyridoxine
Authors:GM Escandar  AJ BystolAD Campiglia
Abstract:A simple and highly selective method for the determination of piroxicam and pyridoxine (vitamin B6) in pharmaceutical formulations is presented. The approach is based on the combination of solid-phase extraction (SPE) and room-temperature fluorimetry (RTF). SPE under optimum pH conditions provides the separation between piroxicam and pyridoxine. The selectivity of analysis, the analytical figures of merit, and the accuracy of the method are demonstrated with the determination of piroxicam and pyridoxine in several pharmaceutical preparations.
Keywords:Room-temperature fluorimetry  Solid-phase extraction  Piroxicam  Pyridoxine
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