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Encoded peptide libraries and the discovery of new cell binding ligands
Authors:Svensen Nina  Díaz-Mochón Juan José  Bradley Mark
Affiliation:School of Chemistry, EastChem, The University of Edinburgh, Joseph Black Building, West Mains Road, Edinburgh, EH9 3JJ, UK.
Abstract:Cells over-expressing integrins or CCR6 were incubated on a DNA microarray, pre-hybridized with a 10,000 member PNA-encoded peptide library allowing novel cell specific ligands for integrins and CCR6 to be identified.
Keywords:
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