Use of cerny epoxides for the accelerated synthesis of glycosaminoglycans |
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| Authors: | Arndt Sabine Hsieh-Wilson Linda C |
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| Institution: | Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA. |
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| Abstract: | reaction: see text]. 1,6:2,3-Dianhydrohexopyranoses (Cerny epoxides) are versatile intermediates for the synthesis of glycosaminoglycans. Complex heparan and chondroitin sulfate disaccharide synthons can be assembled from a single common precursor in a short sequence of steps. |
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