Design and synthesis of a new class of arginine analogues with an improved anion binding site in the side chain |
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Authors: | Schmuck Carsten Geiger Lars |
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Institution: | Institut für Organische Chemie, Universit?t Würzburg, Am Hubland, 97074, Würzburg, Germany. schmuck@chemie.uni-wuerzburg.de |
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Abstract: | Replacing the guanidinium group in arginine (1) by a guanidiniocarbonyl pyrrole moiety provides a new class of artificial amino acids (2), that can be used as building blocks in standard solid phase peptide synthesis. |
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