Soft-landing of peptide ions onto self-assembled monolayer surfaces: an overview |
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Authors: | Laskin Julia Wang Peng Hadjar Omar |
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Institution: | Fundamental Sciences Division, Pacific Northwest National Laboratory, P.O. Box 999 K8-88, Richland, WA 99352, USA. Julia.Laskin@pnl.gov |
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Abstract: | This review is focused on what has been learned in recent research studies concerned with fundamental aspects of soft-landing and reactive landing of peptide ions on self-assembled monolayer surfaces (SAMs). Peptide ions are particularly attractive model systems that provide important insights on the behavior of soft landed proteins, while SAMs provide a convenient and flexible platform for tailoring the interfacial properties of metals and semiconductor surfaces. Deposition of mass-selected ions on surfaces is accompanied by a number of processes including charge reduction, neutralization, covalent and non-covalent binding, and thermal desorption of ions and molecules from the substrate. Factors that affect the competition between these processes are discussed. |
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