Synthesis of 2-N,N-dimethylaminomethyl-2,3,3a,12b-tetrahydrodibenzo-[b,f]furo[2,3-d]oxepin derivatives as potential anxiolytic agents |
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| Authors: | Trabanco Andrés Avelino Alonso José Manuel Andrés José Ignacio Cid José Maria Fernández Javier Iturrino Laura Megens Anton |
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| Affiliation: | Johnson & Johnson Pharmaceutical Research & Development, a Division of Janssen-Cilag SA, Toledo, Spain. atrabanc@prdes.jnj.com |
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| Abstract: | New synthesis approaches that have led to a series of novel tetrahydrodibenzo[b,f]furo[2,3-d]oxepin derivatives are described. According to preliminary data these novel tetracycles can be useful intermediates for the preparation of potential new therapeutic agents. |
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