Limit of Detection in Test Methods of Analysis with Visual Indication: Affecting Factors |
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| Authors: | E. A. Reshetnyak N. A. Nikitina L. P. Loginova V. M. Ostrovskaya |
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| Affiliation: | (1) Department of Chemistry, Karazin National University, pl. Svobody 4, Kharkov, 61077, Ukraine;(2) Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Sciences, Leninskii pr. 31, Moscow, 119991, Russia |
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| Abstract: | A statistical approach to evaluating the limit of detection (cmin) was used for studying 12 test systems with visual indication based on reagent indicator paper, polyurethane foam, gelatin films, powdered methylsilicic acid, and reagent solutions. It was proposed to characterize the quality of test systems by relative width of the region of an unreliable response. The dependence of the characteristics of test systems on the material of the support, the type of analytical reaction, the conditions of color observation in the test system, and the number of observations were discussed. |
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