Synthesis of new esters and amides of cephalosporin G |
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Authors: | I V Serkov V V Bezuglov |
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Institution: | (1) Institute of Physiologically Active Compounds, Russian Academy of Sciences, 142432 Moscow Oblast’, Chernogolovka, Severnyi pr., 1;(2) M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, ul. Miklukho-Maklaya, 16/10 |
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Abstract: | Synthetic methods for cephalosporin G derivatized at the carboxyl were developed. Dinitroglycerine, acetoxymethyl, and choline
esters of cephalosporin G and its amide in addition to amides of cephalosporin G with glutamic acid and arginine were synthesized.
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Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 85–88, January–February, 2007. |
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Keywords: | antibiotics cephalosporin G amides esters dinitroglycerine acid fluorides |
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