Comparison of elemental composition of hair between osteoporotic and normal women by instrumental neutron activation analysis |
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Authors: | L G Stephens-Newsham M J M Duke T R Overton D Ng |
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Institution: | (1) SLOWPOKE Reactor Facility, University of Alberta, T6G 2G3 Edmonton, Alberta, (Canada);(2) Department of Applied Sciences in Medicine, University of Alberta, T6G 2G3 Edmonton, Alberta, (Canada) |
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Abstract: | Instrumental neutron activation analysis (INAA) was carried out on hair samples from a group of twenty patients undergoing a study of osteoporosis. Half of these were judged normal. Fourteen elements were measured but only calcium was found to have a correlation with the disease state. Calcium levels in hair were significantly lower (99% confidence level) in patients with osteoporosis. Conversely, calcium levels in the blood of osteoporotic patients were significantly higher (95% confidence level) than those in normals. Though the group studied was small it is felt that the levels of calcium in hair may be of value in diagnosing osteoporosis. |
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