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THE SEPARATION,PURIFICATION AND DECOLORIZATION OF NEW ANTIBIOTICS—MILUPEINAN USING ADSORPTION RESIN
引用本文:ZHANGYifeng YINShougen 等.THE SEPARATION,PURIFICATION AND DECOLORIZATION OF NEW ANTIBIOTICS—MILUPEINAN USING ADSORPTION RESIN[J].反应性高分子(英文版),2002,11(1):85-90.
作者姓名:ZHANGYifeng  YINShougen
作者单位:ZHANG Yifeng,GUO Hong,ZHANG Guangming(Institute of Taitai Pharmaceutical Co. Ltd, Shengzhen 518057, China);YAN Xiuyun,YIN Shougen,ZHANG Zhengpu(State Key Lab. of Functional Polymeric Materials for Adsorption and Separation Institute of Polymer Chemistry, Nankai University, Tianjin 300071, China)   
摘    要:

关 键 词:抗生素  吸附树脂  抗菌素  Milupeinan  分离  净化  脱色

THE SEPARATION, PURIFICATION AND DECOLORIZATION OF NEW ANTIBIOTICS-MILUPEINAN USING ADSORPTION RESIN
ZHANG Yifeng,GUO Hong,ZHANG Guangming,YAN Xiuyun,YIN Shougen,ZHANG Zhengpu.THE SEPARATION, PURIFICATION AND DECOLORIZATION OF NEW ANTIBIOTICS-MILUPEINAN USING ADSORPTION RESIN[J].Chinese Journal of Reactive Polymers,2002,11(1):85-90.
Authors:ZHANG Yifeng  GUO Hong  ZHANG Guangming  YAN Xiuyun  YIN Shougen  ZHANG Zhengpu
Institution:1. Institute of Taitai Pharmaceutical Co. Ltd, Shengzhen 518057, China
2. State Key Lab. of Functional Polymeric Materials for Adsorption and Separation Institute of Polymer Chemistry, Nankai University, Tianjin 300071, China
Abstract:Adsorption resin AAS was used for the separation and purification of milupeinan (M-13)from its mother liquor. The good adsorption property of AAS adsorption resin was found formilupeinan (M-13) compared with the Diaion CHP 20p. When acetone and water (2:1 in volume)were used as desorption reagents, it was found that 3 times of bed volume of the desorption reagentswould make the AAS resin which was saturately adsorpted M-13 desorption completely.Also a macroporous anion exchange resin (Poly-4-vinylpyridine type) D-280 was used for thedecolourization from M-13 solution. Good results was given when the sr=1~2.
Keywords:AAS adsorption resin  D-280 decoloulization resin  Milupeinan (M-13)
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