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Thiazolidine-2,4-dione-linked ciprofloxacin derivatives with broad-spectrum antibacterial,MRSA and topoisomerase inhibitory activities |
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| Authors: | Aziz Hossameldin A. El-Saghier Ahmed M. M. Badr Mohamed Abuo-Rahma Gamal El-Din A. Shoman Mai E. |
| Affiliation: | 1.Department of Medicinal Chemistry, Faculty of Pharmacy, Minia University, Minia, 61519, Egypt ;2.Sohag Cancer Center, Sohag, Egypt ;3.Department of Chemistry, Faculty of Science, Sohag University, Sohag, Egypt ;4.Department of Biochemistry, Faculty of Pharmacy, Menoufia University, Menoufia, Egypt ;5.Department of Pharmaceutical Chemistry, Deraya University, New Minia, Minia, Egypt ; |
| Abstract: | Molecular Diversity - A series of ciprofloxacin/thiazolidine-2,4-dione hybrids 3a-m were prepared and identified by IR, 1HNMR, 13CNMR and elemental analysis. The antibacterial activity results of... |
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