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Application of NMI-TfCl-mediated amide bond formation in the synthesis of biologically relevant oxadiazole derivatives employing less basic (hetero)aryl amines
Authors:Rajendra  Merla Arjuna  Naseem  Muhammad  Joy  Muthipeedika Nibin  Sunil  K  Sajith  Ayyiliath Meleveetil  Howari  Fares  Nazzal  Yousef  Xavier  Cijo  Alshammari  Mohammed B  Haridas  Karickal Raman
Institution:1.Department of Chemistry, SSIT, Sri Siddhartha Academy of Higher Education, Tumkur, Karnataka, 572107, India
;2.College of Natural and Health Sciences, Zayed University, PO Box 144534, Khalifa City, Abu Dhabi, UAE
;3.Innovation Center for Chemical and Pharmaceutical Technologies, Institute of Chemical Technology, Ural Federal University, 19 Mira Street, Yekaterinburg, Russia, 620002
;4.School of Chemical Sciences, Kannur University, Payyanur Campus, Edat, P.O. 670327, Kannur, Kerala, India
;5.Chemistry Department, College of Science and Humanities, Prince Sattam Bin Abdulaziz University, 11942, P.O. Box 83, Al-Kharij, Saudi Arabia
;
Abstract:Molecular Diversity - We herein report a modified methodology for the synthesis of some oxadiazoles linked to amides under mild conditions. The developed protocol using NMI-TfCl has been found to...
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