New fused pyrroles with rA1/A2A antagonistic activity as potential therapeutics for neurodegenerative disorders |
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Authors: | van Vuuren Nadia Janse van Rensburg Helena D. Janse Terre’Blanche Gisella Legoabe Lesetja J. |
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Affiliation: | 1.Centre of Excellence for Pharmaceutical Sciences, North-West University, Private Bag X6001, Potchefstroom, 2520, South Africa ;2.Pharmaceutical Chemistry, School of Pharmacy, North-West University, Private Bag X6001, Potchefstroom, 2520, South Africa ; |
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Abstract: | Molecular Diversity - In a pilot study, eleven pyrrolopyridine and pyrrolopyrimidine derivatives (specifically, 7-azaindole and 7-deazapurine derivatives) were synthesised by Suzuki cross-coupling... |
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