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Design,synthesis and SAR of antitubercular benzylpiperazine ureas |
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| Authors: | Satish Sohal Chitral Rohan Kori Amitkumar Sharma Basantkumar Puttur Jayashree Khan Afreen A. Desle Deepali Raikuvar Kavita Korkegian Aaron Martis Elvis A. F. Iyer Krishna R. Coutinho Evans C. Parish Tanya Nandan Santosh |
| Affiliation: | 1.Ambernath Organics Pvt. Ltd., 222, The Summit Business Bay, Andheri (E), Mumbai, 400 093, India ;2.Department of Pharmaceutical Chemistry, Bombay College of Pharmacy, Kalina, Santacruz (E), Mumbai, 400 098, India ;3.TB Discovery Research, Infectious Disease Research Institute, 1616 Eastlake Avenue E, Suite 400, Seattle, WA, 98102, USA ; |
| Abstract: | Molecular Diversity - N-furfuryl piperazine ureas disclosed by scientists at GSK Tres Cantos were chosen as antimycobacterial hits from a phenotypic whole-cell screen. Bioisosteric replacement of... |
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