|
|||||
|
|
Design,antihuman immunodeficiency activity and molecular docking studies of synthesized 2-aryl and 2-pyrimidinyl pyrrolidines |
|
| Authors: | Gasparyan Sahak P Martirosyan Ashot H Alexanyan Marina V Harutyunyan Gohar K Chilingaryan Garri V Coats Steve Schinazi Raymond F |
| Institution: | 1.Scientific and Technological Centre of Organic and Pharmaceutical Chemistry, Institute of Fine Organic Chemistry, National Academy of Sciences of RA, Azatutyan Avenue 26, 0014, Yerevan, Republic of Armenia ;2.Department of Medical Biochemistry and Biotechnology, Institute of Biomedicine and Pharmacy, Russian-Armenian Niversity, Hovsep Emin Street 123, 0051, Yerevan, Republic of Armenia ;3.Center for AIDS Research, Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, 1760 Haygood Drive, Atlanta, GA, 30322, USA ; |
| Abstract: | Molecular Diversity - A series of thirty-one new compounds were synthesized and evaluated for their anti-HIV-1 and cytotoxicity activity. Of these, twelve were found to be inhibitors of HIV... |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ | |