Circulardichroismus- und13C-NMR-Untersuchungen zur Dissoziation von Aminosäuren

The dissociation of amino acids such, as histidine, methionine and of shorter peptides can be studied by pulse Fourier transform.¹³C-NMR spectroscopy. The pH-dependencies of the¹³C-signals show directly the changes of the electronic charge densities of all carbon atoms caused by the dissociation process. Additional comparative studies of the pH and temperature dependencies of the CD spectra and the¹H-NMR spectra give now better information on the steric and electronic changes due to the dissociation of polyfunctional amino acids and oligopeptides.