Coordination chemistry of oxovanadium(V) complexes with active Schiff bases: synthetic,spectral, and antimicrobial approach |
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Authors: | R Garg N Fahmi R V Singh |
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Institution: | (1) Department of Chemistry, University of Rajasthan, Jaipur, 302004, India |
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Abstract: | The Schiff bases, 3-(indolin-2-one)hydrazinecarbothioamide (L1H), 3-(indolin-2-one)hydrazinecarboxamide (L2H), 5,6-dimethyl-3-(indolin-2-one)hydrazinecarbothioamide (L3H), and 5,6-dimethyl-3-(indolin-2-one)hydrazinecarboxamide (L4H), have been synthesized by the condensation of 1
H-indol-2,3-dione and 5,6-dimethyl-1H-indol-2,3-dione with the corresponding hydrazinecarbothioamide and hydrazinecarboxamide, respectively. The complexes of oxovanadium
and ligands have been characterized by elemental analyses, melting points, conductance measurements, molecular weight determinations,
and IR, 1H NMR and UV spectral studies. These studies showed that the ligands coordinated to the oxovanadium in a monobasic bidentate
fashion through oxygen or sulfur and the nitrogen donor system. Thus, penta-and hexacoordinated environment around the vanadium
atom has been proposed. All the complexes and their parent organic moieties have been screened for their biological activity
on several pathogenic fungi and bacteria and were found to possess appreciable fungicidal and bactericidal properties.
The article was submitted by the authors in English. |
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