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EEG topography-specific BOLD changes: a continuous EEG-fMRI study in a patient with focal epilepsy |
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| Authors: | Mirco Cosottini Ilaria Pesaresi Patrizia Maritato Gina Belmonte Arianna Taddei Ferdinando Sartucci Mario Mascalchi Luigi Murri |
| Institution: | 1. Department of Neuroscience University of Pisa, 56100 Pisa, Italy;2. Department of Radiology University of Pisa, 56100 Pisa, Italy;3. Medical Physics University of Pisa, 56100 Pisa, Italy;4. Department of Clinical Physiopathology, University of Florence, 50134 Florence, Italy |
| Abstract: | Blood oxygenation level dependent (BOLD) response related to interictal activity was evaluated in a patient with post-traumatic focal epilepsy at repeated continuous electroencephalogram (EEG)-functional magnetic resonance imaging examinations. Lateralized interictal EEG activity induced a main cluster of activation co-localized with the anatomical lesion. Spreading of EEG interictal activity to both frontal lobes evoked bilateral clusters of activation indicating that topography of BOLD response might depend on the spatial distribution of epileptiform activity. |
| Keywords: | Focal epilepsy Interictal epileptiform activity Continuous EEG-fMRI BOLD response |
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