Methylations: a radical mechanism |
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Authors: | Fontecave Marc |
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Affiliation: | Institut de Recherches en Technologie et Sciences pour le Vivant IRTSV-LCBM, UMR 5249 CEA/CNRS/UJF, CEA-Grenoble, France. mfontecave@cea.fr |
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Abstract: | On the basis of labeling experiments, Grove et?al. (2011) have shown how an electrophilic carbon (from an?RNA adenosine) can be methylated by S-adenosylmethionine-dependent methyltransferases though an original radical mechanism. |
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