Influence of La3+ on the Phase Behavior and the Pluidity of Phospholipid Bilayers |
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| Authors: | LI Xin-min ZHAO Bing NI Jia-zuan WU Ying XU Wei-qing CHEN Jian-Wen HUANG Fen |
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| Institution: | 1. Laboratory of Rare Earth Chemistry and Physics, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, P. R. China;
2. Key Laboratory for Molecular Spectra and Structure, Jilin University, Changchun, 130023 P. R. China;
3. State Key Laboratory of Biomacromolecuies, Institute of Biophysics Chinese Academy of Sciences, Beijing, 100101, P. R. China |
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| Abstract: | The influence of La3+ on the phase behavior and the fluidity of the negatively charged phospholipid dipalmitoylphosphatidylglycerol(DPPG) bilayers was studied by differential scanning calorimetry (DSC) and FT-Raman spectroscopy. La3+, induced a phase separation of DPPG bilayers, and formed three peaks. La3+ increased the phase transition temperature of the new peaks, broadened the half width of the DSC signal, and stabilized a gel phase relative to a crystalline phase of DPPG bilayers. La3+ was shown to increase interchain order and intermolecular ordering of the lipid lattice, and decreased the fluidity of DPPG bilayers. |
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| Keywords: | Phase bahavior Phospholipid Dipalmitoylphosphatidylglycerol |
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