Abstract: | A convenient method has been developed for the interaction of dialkyl phosphites with 1,6,8-trihydroxy-3-methylanthraquinone (emodin) under the conditions of the Todd—Atherton reaction. It has been shown that the -hydroxy groups of emodin are not phosphorylated at an equimolar ratio of emodin and dialkyl phosphite. The phosphorylation of 7-bromo-1,6,8-trihydroxy-3-methylanthraquinone with potassium dialkyl phosphorothioates has been studied. The reaction takes place at the sulfur atom, with the formation of of the product of S-alkylation.Al-Farabi Kazakh State National University, Almaty. Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 212–216, March–April, 1994. |