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Pd-catalyzed one-pot coupling of allylamines, activated alkenes, and unsaturated halides (or triflate): an atom efficient synthesis of highly functionalized pyrrolidines
Authors:Luc Martinon,Sté  phane Azoulay,E. Peter Kü  ndig
Affiliation:a Laboratoire de Chimie Organique 1, CNRS UMR 5181, Université Claude Bernard-Lyon 1, CPE, 43 Bd du 11 Novembre 1918, F-69622 Villeurbanne, France
b Department of Organic Chemistry, University of Geneva, 30 Quai Ernest Ansermet, CH-1211 Geneva, Switzerland
Abstract:A Pd-catalyzed three-component assembling of highly functionalized 4-benzyl-(and allyl-)pyrrolidines was achieved based on a combination of allyl amines, gem-diactivated alkenes, and unsaturated halides (or triflate).
Keywords:Palladium   Multicomponent reaction   Carbocyclization   Pyrrolidines
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