Pd-catalyzed one-pot coupling of allylamines, activated alkenes, and unsaturated halides (or triflate): an atom efficient synthesis of highly functionalized pyrrolidines |
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Authors: | Luc Martinon,Sté phane Azoulay,E. Peter Kü ndig |
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Affiliation: | a Laboratoire de Chimie Organique 1, CNRS UMR 5181, Université Claude Bernard-Lyon 1, CPE, 43 Bd du 11 Novembre 1918, F-69622 Villeurbanne, France b Department of Organic Chemistry, University of Geneva, 30 Quai Ernest Ansermet, CH-1211 Geneva, Switzerland |
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Abstract: | A Pd-catalyzed three-component assembling of highly functionalized 4-benzyl-(and allyl-)pyrrolidines was achieved based on a combination of allyl amines, gem-diactivated alkenes, and unsaturated halides (or triflate). |
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Keywords: | Palladium Multicomponent reaction Carbocyclization Pyrrolidines |
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