Partial synthesis of 23-hydroxyursolic acid isolated from medicinal plants of the Rubiaceae family |
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Authors: | Bore Lothar Honda Tadashi Gribble Gordon W |
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Institution: | Department of Chemistry, Dartmouth College, Hanover, New Hampshire 03755-3564, USA. |
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Abstract: | 23-Hydroxyursolic acid (2), previously isolated from medicinal plants of the Rubiaceae family, was synthesized in ten steps via methyl 23-hydroxy-3-oxours-12-en-28-oate (5) from commercially available ursolic acid (6). |
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