Ruthenium(II) polypyridyl complexes as carriers for DNA delivery |
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Authors: | Bhat Satish S Kumbhar Avinash S Kumbhar Anupa A Khan Ayesha Lönnecke Peter Hey-Hawkins Evamarie |
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Affiliation: | Department of Chemistry, University of Pune, Pune- 411007, India. |
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Abstract: | Two novel water soluble ruthenium(II) complexes [Ru(bpy)(2)(bqbg)](2+) and [Ru(phen)(2)(bqbg)](2+) have been structurally characterized and their DNA condensation activity, cytotoxicity, and cellular uptake studies of DNA condensates as potential non-viral DNA carriers were evaluated. |
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