| Preparation of Functional Magnetic Nanoparticles and its Application in Diagnostic Analysis |
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| 作者姓名： | Qiong CHENG Tu Zhi PENG Ai Li LIU |
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| 作者单位： | [1]Department of Chemistry, Xixi Campus,Zhejiang University,Hangzhou 310028 [2]College of biological and Chemical Engineering,Jiaxing Coliege, Jiaxing 314001 |
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| 摘 要： | The magnetic nanoparticles modified with carboxyl functional group were synthesized and characterized. These nanoparticles covalently bound with hepatitis B surface antibody（HBsAb）, were used to detect hepatitis B surface antigen （HBsAg） in immunovoltammetry. The detection limit was found to be 0.06 ng/mL, which is much higher than that of enzyme-linked immunosorbent assay （ELISA） used in clinical analysis.
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| 关 键 词： | 羟基 磁性纳米颗粒技术 诊断技术 合成方法 电化学 |
| 收稿时间： | 2004-08-27 |
Preparation of Functional Magnetic Nanoparticles and its Application in Diagnostic Analysis |
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| Qiong CHENG Tu Zhi PENG Ai Li LIU.Preparation of Functional Magnetic Nanoparticles and its Application in Diagnostic Analysis[J].Chinese Chemical Letters,2005,16(8):1059-1062. |
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| Authors: | Qiong;CHENG;Tu;Zhi;PENG;Ai;Li;LIU |
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| Abstract: | The magnetic nanoparticles modified with carboxyl functional group were synthesized and characterized. These nanoparticles covalently bound with hepatitis B surface antibody (HBsAb), were used to detect hepatitis B surface antigen (HBsAg) in immunovoltammetry. The detection limit was found to be 0.06 ng/mL, which is much higher than that of enzyme-linked immunosorbent assay (ELISA) used in clinical analysis. |
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| Keywords: | Functional magnetic nanoparficles synthesize characterization immunoassay electro chemical detection |
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