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An efficient one-pot synthesis of coumarin-amino acid derivatives as potential anti-inflammatory and antioxidant agents |
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| Authors: | Mamata Devendra Naik Vijay Kumar M Revanasiddappa BC |
| Institution: | 1. Department of P.G. Studies and Research in Industrial Chemistry, Jnanasahyadri, Kuvempu University, Shimoga, India;2. Department of Pharmaceutical Chemistry, NGSM Institute of Pharmaceutical Sciences, NITTE, Mangalore, India |
| Abstract: | AbstractA series of seven coumarinyl-amino acid ester conjugates have been synthesized and characterized by NMR (1H and 13C) and mass spectra. Further, the compounds were investigated for their therapeutic applications such as anti-inflammatory and antioxidant activities. Among the synthesized compounds most of the analogs showed good efficiency compared with the standard. |
| Keywords: | Amino acid ester anti-inflammatory activity antioxidant activity conjugates coumarin-3-carboxylic acid |