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Total synthesis of (3R, 4S)-4-hydroxylasiodiplodin |
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| Authors: | G Nagendra Reddy Mura Reddy Gudisela |
| Institution: | 1. Department of Chemistry, Koneru Lakshmaiah Education Foundation, Guntur, India;2. PS3 Laboratories LLP, Hyderabad, India |
| Abstract: | AbstractAn alternative and concise total synthesis of (3?R, 4S)-4-Hydroxylasiodiplodin has been reported from inexpensive and commercially available 6-heptenal and Orsellinic acid starting materials. The key steps involved in the synthesis are Wittig reaction, Sharpless epoxidation, Yamaguchi esterification and ring-closing metathesis (RCM). |
| Keywords: | (3R 4S)-4-hydroxylasiodiplodin Lasiodiplodins Wittig reaction Yamaguchi esterification and ring-closing metathesis (RCM) |