Iodine(III)-catalyzed benzylic oxidation by using the (PhIO)n/Al(NO3)3 system |
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| Authors: | Berencie Yahuaca-Juárez Gerardo González Marco A. Ramírez-Morales Calara Alba-Betancourt Martha A. Deveze-Álvarez Claudia L. Mendoza-Macías |
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| Affiliation: | 1. Facultad de Químicofarmacobiología, Universidad Michoacana de San Nicolás de Hidalgo, Morelia , Michoacán , México;2. División de Ciencias Naturales y Exactas Departamento de Química, Universidad de Guanajuato, Gto , México |
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| Abstract: | AbstractThe first iodine(III)-based procedure for the benzylic oxidation of different arenes is described by using the (PhIO)n/Al(NO3)3 system under catalytic conditions leading to the formation of the corresponding carbonyl derivatives. The method proceeds under mild, operationally simple, room temperature, short reaction times, and open flask conditions. In light of the organocatalysis relevance and the novelty of our protocol, we wish to communicate our initial results of this novel oxidation. |
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| Keywords: | Benzylic oxidation Csp 3-H activation iodine(III)-catalysis organocatalyst |
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