A new isoprenyl phenyl ether compound from mangrove fungus |
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Authors: | Changlun Shao Zhiyong Guo Hong Peng Guangtian Peng Zhongjing Huang Zhigang She Yongcheng Lin Shining Zhou |
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Affiliation: | (1) School of Chemistry and Chemical Engineering, Sun Yat-Sen (Zhongshan) University, 510275 Guangzhou, P.R. China;(2) College of Life Science, Sun Yat-Sen (Zhongshan) University, 510275 Guangzhou, P.R. China |
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Abstract: | A new isoprenyl phenyl ether, 3-hydroxy-4-(3-methylbut-2-enyloxy)benzoic acid methyl ester (1), together with 4-hydroxybenzoic acid (2), 2-hydroxy-6-methylbenzoic acid (3), and 4-hydroxy-3-methoxybenzoic acid (4) were isolated from Mangrove fungus (No. B60) from the South China Sea. The structures of the compounds were established on the basis of NMR spectroscopic and mass spectrometric data. In the preliminary bioassay, compound 1 exhibited antibacterial and antifungal activities. Compound 1 also inhibited cytotoxicity to the hepG2 cell line with an IC50 value of 10.0 μg/mL. Published in Khimiya Prirodnykh Soedinenii, No. 4, pp. 313–314, July–August, 2007. |
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Keywords: | marine fungi biological activity isoprenyl phenyl ether |
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