Novel method for synthesizing spiro[4.5]cyclohexadienones through a Pd-catalyzed intramolecular ipso-Friedel-Crafts allylic alkylation of phenols |
| |
| Authors: | Nemoto Tetsuhiro Ishige Yuta Yoshida Mariko Kohno Yuta Kanematsu Mutsumi Hamada Yasumasa |
| |
| Institution: | Graduate School of Pharmaceutical Sciences, Chiba University, 1-33, Yayoi-cho, Inage-ku, Chiba 263-8522, Japan. |
| |
| Abstract: | The first successful Pd-catalyzed intramolecular ipso-Friedel-Crafts allylic alkylation of phenols, which provided a new access to spiro4.5]cyclohexadienones, is described. The present method could be applied to catalytic enantioselective construction of an all-carbon quaternary spirocenter. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
