Lactam acetals |
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Authors: | V. G. Granik A. M. Zhidkova T. F. Vlasova R. G. Glushkov Yu. N. Sheinker |
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Affiliation: | 1. S. Ordzhonikidze All-Union Scientific-Research Pharmaceutical-Chemistry Institute, Moscow
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Abstract: | The rate of deuteration of 1-methyl-2-aryliminolactams depends on the electronic character of the substituent in the benzene ring and on the size of the lactam ring. Deuterium exchange proceeds at the highest rate in piperidine derivatives that have electron-donor substituents in the benzene ring. |
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