Tyrosinase inhibitory potential of natural products isolated from various medicinal plants |
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| Authors: | Azizuddin Khan A Majeed Choudhary M Iqbal |
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| Affiliation: | Department of Chemistry, Federal Urdu University for Arts, Science and Technology,Gulshan-e-Iqbal Campus, Karachi 75300, Pakistan. azizpobox1@yahoo.com |
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| Abstract: | Seven secondary metabolites, p-hydroxybenzoic acid (1), 3,4-dihydroxybenzoic acid (2), ferulic acid (3), 2,6-dimethoxy-4-hydroxy acetophenone (4), lupeol (5), 2'-O-ethylmurrangatin (6) and hibiscetin heptamethyl ether (7) were the natural products isolated from various medicinal plants. Their structures were identified by spectral comparison with previously reported data. The compounds 1-7 were screened for their tyrosinase-inhibitory activity. The compound p-hydroxybenzoic acid (1) was found to have potent activity against tyrosinase enzyme, whereas lupeol (5) showed significant activity. |
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