| Abstract: | The thermal transformations of cardiac glycosides in neutral alcoholic solutions have been investigated. The kinetics of their acidless hydrolysis at 100 and 142°C and the activation energy of the process have been studied. The possibility has been shown of the stepwise hydrolysis of natural trisdigitoxosides with the production of difficulty available mono- and bisdigitoxosides. The following were used as the objects of investigation: convallatoxin, glucostrophanthidin, cheirotoxin, desglucocheirotoxin, erycordin, erysimin, erysimoside, digitoxin, and cymarin.All-Union Scientific-Research Institute of Drug Chemistry and Technology, Kharkov. Kharkov State Pharmaceutical Institute. Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 62–64, January–February, 1991. |
