Synthesis and properties of a fluorescent derivative of quinoline —N-[N-(6-aminohexyl)-5-dimethylamino-1-naphthylsulfonamido]-8-(N-methyl-N-2-propynyl)aminomethylquinoline-5-carboxamide

The synthesis of quinoline derivatives that contain a fluorogenic grouping by condensation of 8-(N-methyl-N-carbobenzoxy)aminomethylquinoline-5-carboxylic acid azide with N-(6-aminohexyl)-5-dimethylaminonaphthalenesulfonamide is described. The resulting carboxamide was subjected to hydrogenolysis, and subsequent reaction with propargyl bromide led to the title compound.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No, 6, pp. 789–792, June, 1982.