Synthesis of a Novel α-Methylene-β-carboxy-γ-thiobutyrolactones |
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作者姓名: | Xiao Kui WANG Jian Lei KANG Song LI |
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作者单位: | Beijing Institute of Pharmacology & Toxicology, Beijing 100850 |
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基金项目: | This work was supported by the National High Technology Research and Development Program of China (863 project: 2003AA235010) and the National Basic Research Program of China (973 project: 2004CB518908). |
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摘 要: | A new series compounds, α-methylene-β-carboxy-γ-thiobutyrolactones, have been prepared and their biological evaluation in vitro and in vivo have been described. The structures of these compounds were confirmed by ^1H NMR and FAB-MS spectra.
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关 键 词: | α-亚甲基-β-羧基-γ-内酯 合成方法 脂肪酸 代谢作用 |
收稿时间: | 2005-03-02 |
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