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A Green and Highly Efficient Protocol for Catalyst‐free Knoevenagel Condensation and Michael Addition of Aromatic Aldehydes with 1,3‐Cyclic Diketones in PEG‐400
Authors:Nemati Firouzeh  Kiani Hossein
Affiliation:Department of Chemistry, Faculty of Science, Semnan University, Semnan, Iran
Abstract:A convenient, highly efficient and green approach for synthesis of tetraketones from aromatic aldehydes with dimedone and 1,3‐indanedione at room temperature in PEG‐400 is described. The use of PEG‐400 as the reaction medium and avoiding the use of any catalyst makes the process environmentally benign. Seven new compounds are reported.
Keywords:Michael addition  green chemistry  polyethelene glycol  Knoevenagel condensation  dimedone  1,3‐Indanedione
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