| Enantioseparation of Dencichine and D-Isomer on L-Cysteine Derivative Phase by Ligand-exchange Chromatography |
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| 作者姓名： | Yan Shun MA Qing Hua MENG Hong Yu SHI Yuan De LONG Tian Bao HUANG |
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| 作者单位： | Yan Shun MA1，2，Qing Hua MENG1，2，Hong Yu SHI1，2，Yuan De LONG1，Tian Bao HUANG1 1Chengdu Institute of Organic Chemistry，Chinese Academy of Sciences，Chengdu 610041 2Graduate School of the Chinese Academy of Sciences，Beijing 100049 |
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| 基金项目： | We are grateful to Prof. Zhang Wan LI, Sichuan University, for the gift of L-0DAP and DL-0DAP samples. |
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| 摘 要： | Dencichine (β-N-oxalyl-L-α, β-diaminopropionic acid, L-ODAP), a nonprotein amino acid, is a haemostatic agent present in important Chinese medicinal herbs such as Panax notoginseng, as well as other Panax species1. It was first isolated from the seeds …
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| 关 键 词： | D-异构体 L-半胱氨酸 配位体交换色谱法 结构分析 |
| 收稿时间： | 2005-12-02 |
Enantioseparation of Dencichine and D-Isomer on L-Cysteine Derivative Phase by Ligand-exchange Chromatography |
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| Yan Shun MA Qing Hua MENG Hong Yu SHI Yuan De LONG Tian Bao HUANG.Enantioseparation of Dencichine and D-Isomer on L-Cysteine Derivative Phase by Ligand-exchange Chromatography[J].Chinese Chemical Letters,2006,17(6):807-808. |
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| Authors: | Yan Shun MA Qing Hua MENG Hong Yu SHI Yuan De LONG Tian Bao HUANG |
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| Abstract: | The enantioseparation of dencichine and its D-isomer was achieved on a novel chiral stationary phase via coating N-(2-hydroxyl-3-octoxyl) propyl-S-benzyl-(L)-cysteine on YWG-C18 phase by ligand exchange chromatography. |
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| Keywords: | Dencichine enantioseparation ligand exchange chromatography chiral stationary phase |
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