Surface-modified protein nanospheres as potential antiviral agents |
| |
| Authors: | Dana Baram-Pinto Sourabh Shukla Michal Richman Aharon Gedanken Shai Rahimipour Ronit Sarid |
| |
| Affiliation: | Institute of Nanotechnology and Advanced Materials, Bar-Ilan University, Ramat-Gan 52900, Israel. |
| |
| Abstract: | A novel application of surface-modified protein nanospheres as potential antiviral agents is illustrated. By using a single-step sonochemical process, bovine serum albumin nanospheres were generated, whose surface was covalently conjugated with mercaptoethane sulfonate to chemically and electrostatically mimic cellular heparan sulfate. The nanospheres effectively inhibited HSV-1 infection. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
