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Chemical speciation of nanoparticles surrounding metal-on-metal hips |
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| Authors: | Angela E Goode James M Perkins Ann Sandison Chithra Karunakaran Huikai Cheng David Wall John A Skinner Alister J Hart Alexandra E Porter David W McComb Mary P Ryan |
| Affiliation: | Department of Materials, Imperial College London, London, UK. |
| Abstract: | Spectromicroscopy of tissue surrounding failed CoCr metal-on-metal hip replacements detected corroded nanoscale debris in periprosthetic tissue in two chemical states, with concomitant mitochondrial damage. The majority of debris contained Cr(3+), with trace amounts of oxidised cobalt. A minority phase containing a core of metallic chromium and cobalt was also observed. |
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