Indole derivatives |
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Authors: | N N Suvorov V S Velezheva V V Vampilova |
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Institution: | 1. D. I. Mendeleev Moscow Institute of Chemical Technology, USSR
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Abstract: | 5-(3-Indolylmethyl)barbituric and 5-(3-indolylmethyl)thiobarbituric acids were obtained by condensation of 3-indolylmethylmalonic ester with urea and thiourea in monoglyme (1,2-di-methoxyethane) in the presence of lithium methoxide. The first of the two acids was also obtained by catalytic hydrogenation of 5- (3-indolylmethylene)barbituric acid. |
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