Preparation of 1-aryl-2-methyl-3-carbethoxy-4,5-dioxo-6-bromoindoles |
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Authors: | A N Grinev G Ya Uretskaya N V Arkhangel'skaya S Yu Ryabova T F Vlasova |
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Institution: | 1. S. Ordzhonikidze All-Union Scientific-Research Pharmaceutical Chemistry Institute, Moscow
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Abstract: | 1-Aryl-2-methyl-3-carbethoxy-5-hydroxy-6-bromoindoles are oxidized by nitric acid to 1-aryl-2-methyl-3-carbethoxy-4,5-dioxo-6-bromoindoles, while 1,2-dimethyl-3-carbethoxy-5-hydroxy-6-bromoindole is converted to the 4,6-dinitro derivative under similar conditions. |
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