Research in the isoxazole series |
| |
| Authors: | S D Sokolov T N Egorova P V Petrovskii |
| |
| Institution: | 1. S. Ordzhonikidze All-Union Scientific-Research Pharmaceutical Chemistry Institute, Moscow
|
| |
| Abstract: | The 4-nitro derivative is formed in the nitration of 3,5-diphenylisoxazole (I) in acetic anhydride. Mononitration of isoxazole I in concentrated H2SO4 gave 3-phenyl-5-(p-nitrophenyl)isoxazole, while polynitration gave a mixture of dinitro derivatives, among which 3- (m-nitro-phenyl)-5-(p-nitrophenyl)isoxazole was identified. The structures of the isolated products were established by means of the spectra, by reaction-chromatography methods, and gasliquid chromatography, as well as by a comparison with genuine samples of the two mononitro and four dinitro derivatives of isoxazole I. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
