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Condensation of 2-(acetamido)cyclohexanone with malononitrile
Authors:V. I. Shvedov  M. V. Mezentseva  L. B. Altukhova  A. N. Grinev
Affiliation:1. S. Ordzhonikidze All-Union Scientific-Research Pharmaceutical-Chemistry Institute, Moscow
Abstract:Depending on the conditions, condensation of 2-(acetamido)-cyclohexanone with malononitrile gives 1-acetyl-2-amino-3-cyano-4,5,6,7-tetrahydroindole or 2-amino-3-cyano-4,5,6,7-tetrahydroindole, from which substituted tetrahydropyrimido[1,2-a]indole and tetrahydropyrimido [4,5-b]indole were synthesized.
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