Diversity-oriented approach to pyrrole-imidazole alkaloid frameworks |
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Authors: | Bhandari Manojkumar R Yousufuddin Muhammed Lovely Carl J |
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Affiliation: | Department of Chemistry and Biochemistry, The University of Texas at Arlington, Arlington, Texas 76019, United States. |
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Abstract: | An exploration of imidazolylpropargyl amides as linchpin synthons for the construction of a diverse array of heterocyclic frameworks, many of which are related to those found in the oroidin derived alkaloids, is described. One such intermediate has been used in a formal total synthesis of cyclooroidin. |
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