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Solvent-free Synthesis of Alkylaminophenols via Petasis Boronic Mannich Reaction in One Pot without Catalysts
Authors:Ying Liu  Prof Dr Limin Wang  Yuanyuan Sui  Jianjun Yu
Institution:Laboratory for Advanced Materials, Institute of Fine Chemicals, East China University of Science and Technology, Shanghai 200237, China
Abstract:By using solvent‐free and heat conditions, the Petasis boronic Mannich reaction of salicylaldehydes with various boronic acids and secondary amines without catalyst is described. The alkylaminophenols were obtained in moderate to good yields in a shorter reaction time than the traditional methods.
Keywords:solvent‐free  Petasis boronic Mannich reaction  boronic acids  salicylaldehydes  amines  multicomponent reactions
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