Diabetic wound healing activated by supramolecular cascade reaction
Institution:
1. Key Laboratory of Jiangxi Province for Persistent Pollutants Control and Resources Recycle, Nanchang Hangkong University, Nanchang 330063, China;2. Ultrasound Department, Nanjing Lishui District Hospital of Traditional Chinese Medicine, Nanjing 211200, China;3. Key Laboratory of Mesoscopic Chemistry of MOE, Jiangsu Key Laboratory of Advanced Organic Materials, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China
Abstract:
The nano-supramolecular cascade reactor based on sulfobutylether-β-cyclodextrin, not only displayed glucose-activated radical polymerization to form hydrogel in situ, but also produced hydroxyl radicals for drug-resistant bacteria elimination and wound protection, which successfully achieved diabetic wound healing and in situ therapy.
