| 蛋清蛋白质键合柱及其应用 |
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| 作者姓名： | Yoshiya ODA |
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| 作者单位： | Laboratory of Seeds Finding Technology，Eisai Co. Ltd，Tsukuba Ibaraki 300 2635，Japan |
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| 基金项目： | ThisworkwassupportedbyEisaiCo .Ltd . |
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| 摘 要： | 1 ＩｎｔｒｏｄｕｃｔｉｏｎＭｏｒｅｔｈａｎｈａｌｆｏｆｔｈｅｏｒｇａｎｉｃｃｏｍｐｏｕｎｄｓｍａｒｋｅｔｅｄａｓｄｒｕｇｓａｒｅａｓｙｍｍｅｔｒｉｃｍｏｌｅｃｕｌｅｓ .Ｔｈｅｅｎａｎｔｉｏｍｅｒｓｏｆｄｒｕｇｓ ,ｗｈｉｃｈｈａｖｅａｃｈｉｒａｌｃｅｎｔｅｒｏｆｔｅｎ ,ｈａｖｅｄｉｆｆｅｒｅｎｔｐｈａｒｍａｃｏｌｏｇｉｃａｌａｃｔｉｖｉｔｙｏｒｔｏｘｉｃｉｔｙ ,ｏｗｉｎｇｔｏｄｉｆｆｅｒｅｎｃｅｓｉｎｔｈｅｂｅｈａｖｉｏｒｏｆｅｎａｎｔｉｏｍｅｒｓｉｎｖｉｖｏ .Ｒｅｃｅｎｔｌｙ ,ｅｎａｎｔｉｏｍ…
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Egg White Protein-Bonded Columns and Their Applications |
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| Yoshiya ODA.Egg White Protein-Bonded Columns and Their Applications[J].Chinese Journal of Chromatography,2000,18(6). |
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| Authors: | Yoshiya ODA |
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| Abstract: | Egg white protein bonded columns were developed for HPLC. These columns can be used under aqueous mobile phase and separate various kinds of drug enantiomers. Hyphenated techniques using protein bonded columns with LC/MS and/or column switching have been recognized as integral methods in pharmaceutical research to analyze drug enantiomers. Therefore, these methods are very useful for research fields of pharmacokinetics and pharmacology. |
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| Keywords: | chiral separation LC/MS protein column plasma direct injection column switching |
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